Africa Health Research Institute (AHRI) is a multidisciplinary Research Institute that focuses on fundamental research aimed at improving prevention, diagnosis and treatment of HIV and tuberculosis (TB). The Ndhlovu lab focuses on HIV cure research. South Africa is home to the largest HIV epidemic and the largest treatment program in the world. A cure approach which leads to temporary or permanent HIV remission should therefore be investigated in South Africa. A major barrier to HIV cure is the failure of the current HIV drugs to clear the virus and restore immune function particularly in tissue sanctuary sites such as lymph nodes. The Ndhlovu lab uses excisional lymph node samples obtained from HIV infected individuals to identify microanatomical niches where HIV persists during therapy. These studies will lead to novel strategies of enhancing tissue resident immune responses to facilitate elimination of cryptic HIV infection in tissue sanctuary sites. The Africa Health Research Institute (AHRI) is affiliated with the Ragon Institute of MGH, MIT and Harvard. ... Read more about 216. Africa Health Research Institute, Ndhlovu lab, Durban, South Africa
Did you know there are 18.1 million new cancer patients every year? A study called “World Cancer Report 2018” released by the International Agency for Research on Cancer (IARC) showed recently that the cancer burden has risen from 14 million to 18.1 million new cases and around 9.6 million people died because of it in 2018 alone. OMS’s projections for 2040 are not any better. 29.5 million new cases and 16.3 million deaths on a year basis. Its treatment is long and full of challenges. High patient / doctor ratio, long time period between doctor appointments and the ‘poor memory' factor all contribute to making it very hard for the medical teams to efficiently monitor and track each and every patient’s individual clinical evolution when away from hospitals. For this very reason, there is significant lack of qualified information for out-patients enrolled in mid or long-term cancer treatments. Real World oncological data can truly contribute to life sciences and even guide public policy. ... Read more about 215. WeCancer, São Paulo, Brazil
Perinatal HIV Research Unit (PHRU) is one of Africa’s leading research centres, situated at the Chris Hani Baragwanath Hospital—known locally as ‘Bara’—in Soweto, Johannesburg. PHRU is affiliated with University of the Witwatersrand and engages in research, training, policy-formulation and advocacy concerning HIV-positive people and their children.
Specifically, PHRU conducts adult, paediatric and adolescent HIV treatment research, HIV prevention research and investigations into tuberculosis and other HIV co-infections. In addition to the numerous pharmaceutical and publicly-funded clinical trials PHRU continues to carry out, the unit also conducts important behavioural and social science research, advocates for research access and provides needed care to the people of Soweto.... Read more about 212. Perinatal HIV Research Unit, Soweto, South Africa
The Kwon Laboratory is focused on applying new technologies to the study of immune responses against HIV at mucosal surfaces. Our group in South Africa performs translational research utilizing patient samples from the well-characterized FRESH (Females Rising through Education, Support, and Health) cohort to better understand viral, metagenomic, and adaptive immune factors important for HIV immunity and pathogenesis in the female genital tract. ... Read more about 210. Kwon Lab, Durban, South Africa
Sangath is a non-governmental, not-for-profit research organisation committed to improving health across the lifespan by empowering existing community resources to provide appropriate physical, psychological and social therapies. Its primary focus areas include child development, adolescent and youth health, and mental health and chronic disease. A key element of Sangath’s philosophy is to strengthen state and private sector services by integrating and scaling up affordable and effective interventions through sustainable health systems. Sangath develops and tests contextually appropriate task-sharing interventions that empower low-cost human resources with knowledge and supervision to improve access to mental healthcare.... Read more about 214. Sangath, Goa, India
Y.R. Gaitonde Centre for AIDS Research and Education (YRG CARE) is located in Chennai, the capital of Tamil Nadu state and one of the epicenters of the Indian HIV epidemic. YRG CARE is one of the largest private organizations providing HIV care in India, having treated over 20,000 PLHIV since its founding in 1993. YRG CARE serves patients who are newly diagnosed with HIV as well as experienced patients referred from other HIV providers. The catchment area of YRG CARE primarily includes...